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STAT3 [p Ser727] Antibody (788335) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow
Clone
788335
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC4934U-100UG
Alexa Fluor 405
IC4934V-100UG
Alexa Fluor 488
IC4934G-100UG
Alexa Fluor 532
FAB4934X
Alexa Fluor 594
IC4934T-100UG
Alexa Fluor 647
IC4934R-100UG
Alexa Fluor 700
IC4934N-100UG
Alexa Fluor 750
IC4934S-100UG
Allophycocyanin
FAB4934A
Biotin
FAB4934B
CoraFluor 1
FAB4934CL1
DyLight 350
FAB4934D
DyLight 405
FAB4934E
DyLight 488
FAB4934K
DyLight 550
FAB4934L
DyLight 594
FAB4934M
DyLight 650
FAB4934W
DyLight 680
FAB4934Y
DyLight 755
FAB4934Z
FITC
FAB4934F
HRP
FAB4934H
Janelia Fluor 549
FAB4934I
Janelia Fluor 585
FAB4934JF585
Janelia Fluor 635
FAB4934JF635
Janelia Fluor 646
FAB4934J
Janelia Fluor 669
FAB4934JF669
PE
FAB4934P
PerCP
FAB4934C
Unconjugated
MAB4934
mFluor Violet 450 SE
FAB4934MFV450
mFluor Violet 500 SE
FAB4934MFV500
mFluor Violet 610 SE
FAB4934MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB4934
Carrier Free
MAB4934
Carrier Free
MAB4934-SP
Carrier Free
IC4934V-100UG
Carrier Free
IC4934U-100UG
Carrier Free
IC4934T-100UG
Carrier Free
IC4934S-100UG
Carrier Free
IC4934R-100UG
Carrier Free
IC4934N-100UG
Carrier Free
IC4934G-100UG
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STAT3 [p Ser727] Antibody (788335) [Janelia Fluor® 525] Summary

Immunogen
Phosphopeptide containing the human STAT3 S727 site
Modification
p Ser727
Specificity
Detects human STAT3 when phosphorylated at S727.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
STAT3
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Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for STAT3 [p Ser727] Antibody (788335) [Janelia Fluor® 525]

  • Acute-phase response factor
  • APRFMGC16063
  • DNA-binding protein APRF
  • FLJ20882
  • HIES
  • signal transducer and activator of transcription 3 (acute-phase responsefactor)
  • signal transducer and activator of transcription 3
  • STAT3

Background

Stat3 is a member of a group of proteins (Signal Transduction and Activators of Transcription) that act as both signal transducers for cytokines and growth factors, as well as transcription factors (1,2). Stats are activated by tyrosine phosphorylation in response to different ligands, after which they translocate to the cell nucleus (1). Stat3 is constitutively activated in a number of human tumors (3). Stat3 is activated by phosphorylation on tyrosine 705 which induces dimerization, nuclear translocation, and DNA binding While, Stat3-activated transcription seems to be regulated by serine phosphorylation at serine 727 (4)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol STAT3