Orthogonal Strategies: Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Analysis in human rectum and skeletal muscle tissues. Corresponding ST6GALNAC1 RNA-seq data are presented for the same ...read more
Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human rectum shows strong positivity in Golgi apparatus in glandular cells.
Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human stomach shows strong positivity in Golgi apparatus in glandular cells.
Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human endometrium shows strong positivity in Golgi apparatus in glandular cells.
This antibody was developed against Recombinant Protein corresponding to amino acids: PQTKPSRHQRTENIKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGN
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ST6GALNAC1
Purity
Immunogen affinity purified
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Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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