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ST6GALNAC1 Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Analysis in human rectum and skeletal muscle tissues. Corresponding ST6GALNAC1 RNA-seq data are presented for the same ...read more
Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human rectum shows strong positivity in Golgi apparatus in glandular cells.
Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human stomach shows strong positivity in Golgi apparatus in glandular cells.
Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human endometrium shows strong positivity in Golgi apparatus in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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ST6GALNAC1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: PQTKPSRHQRTENIKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGN
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ST6GALNAC1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence Reported in scientific literature (PMID: 30401951)
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
ST6GALNAC1 Protein (NBP1-87043PEP)
Publications
Read Publications using
NBP1-87043 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for ST6GALNAC1 Antibody

  • alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
  • EC 2.4.99.3
  • GalNAc alpha-2, 6-sialyltransferase I, long form
  • GalNAc alpha-2,6-sialyltransferase I
  • sialyltransferase 7((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminidealpha-2,6-sialyltransferase) A
  • Sialyltransferase 7A
  • Siat7A
  • SIAT7-A
  • ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminidealpha-2,6-sialyltransferase 1
  • ST6GalNAc I
  • ST6GALNAC1
  • ST6GalNAcI
  • ST6GalNAcIHSY11339
  • STYI

Background

Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ST6GALNAC1 Antibody (NBP1-87043)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ICC/IF, IF/IHC.


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(1)
IF/IHC
(1)
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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol ST6GALNAC1