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SNW1 Antibody [Janelia Fluor® 669]

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Product Details

Summary
Reactivity Hu, Mu, Bv, Pm-OrSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

SNW1 Antibody [Janelia Fluor® 669] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 450 and 500 of human Nuclear Receptor Coactivator, 62 kD (SKIIP, SKI Interacting Protein) using the numbering given in entry NP_036377.1 (GeneID 22938).
Predicted Species
Orangutan (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SNW1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SNW1 Antibody [Janelia Fluor® 669]

  • Bx42
  • homolog of Drosophila BX42
  • MGC119379
  • NCoA-62
  • Nuclear protein SkiP
  • Nuclear receptor coactivator NCoA-62
  • nuclear receptor coactivator, 62-kD
  • Prp45
  • PRPF45
  • SKI interacting protein
  • Ski-interacting protein
  • SKIPSKIIP
  • SNW domain containing 1
  • SNW domain-containing protein 1

Background

SNW1, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Array NB100-2367JF669

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Bioinformatics

Gene Symbol SNW1