SMOC-2 Antibody (667713)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

SMOC-2 (secreted modular calcium-binding protein 2; also SMAP2) is a 55 kDa glycoprotein member of the SPARC family of matricellular proteins.  It is widely expressed, perhaps by endothelium, and apparently participates in both growth factor signaling and ECM organization.  Mature human SMOC-2 is 425 amino acids (aa) in length.  It contains one Kazal-like domain (aa 40-84), two thyroglobulin type-1 segments (aa 87-153 and 213-281), and two EF-hand sequences (aa 347-382 and 384‑419).  There are three splice variants.  One shows a 13 aa substitution for aa 442-446, another shows an 11 aa insertion after Thr170, and a third represents a combination of the above two variations.  Over aa 22-446, human SMOC-2 shares 95% aa identity with mouse SMOC-2.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: Functional Assay, IHC.

Showing Publications 1 - 2 of 2.

Publications using MAB5140	Applications	Species
MA Alabiad, OA Harb, N Hefzi, RZ Ahmed, G Osman, AM Shalaby, AA Alnemr, YS Saraya Prognostic and clinicopathological significance of TMEFF2, SMOC-2, and SOX17 expression in endometrial carcinoma Experimental and molecular pathology, 2021-07-31;122(0):104670. 2021-07-31 [PMID: 34339705] (IHC, Human)	IHC	Human
C Gerarduzzi, RK Kumar, P Trivedi, AK Ajay, A Iyer, S Boswell, JN Hutchinson, SS Waikar, VS Vaidya Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation JCI Insight, 2017-04-20;2(8):. 2017-04-20 [PMID: 28422762] (Functional Assay, Mouse)	Functional Assay	Mouse

Array MAB5140

• SMOC-2 Antibodies
• SMOC-2 Lysate
• SMOC-2 Proteins and Enzymes