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S-arrestin Antibody (S128) [DyLight 755]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Eq, PmSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
S128
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 755

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S-arrestin Antibody (S128) [DyLight 755] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Recombinant bovine S-arrestin with the first 20 amino acids of the C-terminus truncated [UniProt# P08168]
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SAG
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Monkey reported in scientific literature (PMID:35024589) .

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for S-arrestin Antibody (S128) [DyLight 755]

  • arrestin 1
  • RP47,48 kDa protein
  • S-antigen; retina and pineal gland (arrestin)
  • S-arrestin
  • visual arrestin

Background

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for S-arrestin Antibody (NBP2-25161IR) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for S-arrestin Antibody (NBP2-25161IR)

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Blogs on S-arrestin.

"Freeze!" - Arrestin Antibodies Used in New Serotonin Syndrome Study
The beta-arrestin family regulate receptor binding of G-proteins, a group of seven transmembrane receptor proteins which includes the adrenergic, dopamine and serotonin receptors. Recently, arrestin antibodies were used in a study into Serotonin Syndr...  Read full blog post.

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Calculators

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Bioinformatics

Gene Symbol SAG