Western blot shows lysates of Jurkat human acute T cell leukemia cell line, EL-4 mouse lymphoblast cell line, and mouse thymus tissue. PVDF Membrane was probed with 0.5 µg/mL of Mouse Anti-Human/Mouse ROR gamma/NR1F3 ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for ROR gamma/RORC/NR1F3 Antibody (600214) [Unconjugated]
MGC129539
NR1F3
Nuclear receptor ROR gamma
Nuclear receptor ROR-gamma
Nuclear receptor RZR gamma
Nuclear receptor RZR-gamma
Nuclear receptor subfamily 1 group F member 3
RAR-Related Orphan Nuclear Receptor Variant 2
RAR-related orphan receptor C
RAR-related orphan receptor gamma
retinoic acid-binding receptor gamma
retinoid-related orphan receptor gamma
Retinoid-related orphan receptor-gamma
ROR gamma
RORC
RORG
RORGMGC129539
RZRG
RZRGRZR-GAMMA
TOR
Background
ROR gamma (Nuclear receptor ROR-gamma), also called RORC and NR1F3, is a member of the NR1 nuclear hormone receptor family. ROR gamma is a DNA binding transcription factor. ROR gamma is 518 amino acids (aa) in length. Deletion in mice implicates ROR gamma as being essential for lymphoid organogenesis and controlling apoptosis during thymopoiesis. Two splice forms differing in the first 24 aa have been found for this gene; isoform 2 deletes aa 1‑21 resulting in an alteration of aa 22‑24. Over aa 1‑100 human RORC shares 96% identity with mouse ROR gamma .
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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