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RBBP6 Antibody

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Immunocytochemistry/Immunofluorescence: RBBP6 Antibody [NBP2-58777] - Staining of human cell line MCF7 shows localization to nuclear speckles.
Immunocytochemistry/ Immunofluorescence: RBBP6 Antibody [NBP2-58777] - Staining of human cell line MCF7 shows localization to nuclear speckles.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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RBBP6 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: TMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RBBP6
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
RBBP6 Recombinant Protein Antigen (NBP2-58777PEP)

Reactivity Notes

Mouse 82%, Rat 83%

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for RBBP6 Antibody

  • E3 ubiquitin-protein ligase RBBP6
  • EC 6.3.2.-
  • MY038
  • P2PR
  • P2P-R
  • p53-associated cellular protein of testis
  • PACTDKFZp761B2423
  • Proliferation potential-related protein
  • Protein P2P-R
  • RB-binding Q-protein 1
  • RBQ1
  • RBQ-1
  • retinoblastoma binding protein 6
  • Retinoblastoma-binding protein 6DKFZp686P0638
  • Retinoblastoma-binding Q protein 1
  • SNAMA

Background

The retinoblastoma tumor suppressor (RBBP6) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RBBP6