Quantikine Immunoassay Control Set 725 for Human PDGF-DD Summary
Additional Information |
For use with catalog number DDD00 |
Source |
N/A |
Inter-Assay |
See PDF Datasheet for details |
Intra-Assay |
See PDF Datasheet for details |
Spike Recovery |
See PDF Datasheet for details |
Sample Volume |
See PDF Datasheet for details |
Gene |
PDGFD |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Quantikine Immunoassay Control Set 725 for Human PDGF-DD
Background
The platelet-derived growth factor (PDGF) family of disulfide-linked dimeric proteins consists of four homodimeric proteins, PDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD, and one heterodimeric protein, PDGF-AB. Members of this protein family act mainly on connective tissue. The dimeric isoforms of PDGF are expressed by different cell types and at different times during embryonic development. All PDGF isoforms are synthesized as inactive precursors and are processed to active forms that contain a PDGF/VEGF cysteine knot domain. Only PDGF-C and PDGF-D, also named spinal cord-derived growth factors SCDGF and SCDGF-B, also contain an N-terminal CUB domain. Mature PDGF dimers bind and induce the homo- or hetero-dimerization of two receptor tyrosine kinases (PDGF R alpha and R beta).
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