Immunohistochemistry-Paraffin: Prokineticin R2/PROKR2 Antibody [NBP1-92290] - Staining of human testis shows moderate to strong cytoplasmic positivity in Leydig cells and cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Prokineticin R2/PROKR2 Antibody [NBP1-92290] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for Prokineticin R2/PROKR2 Antibody
dJ680N4.3
G protein-coupled receptor 73-like 1
GPR73bG-protein coupled receptor 73-like 1
GPR73L1
GPR73L1Kallmann syndrome 3 (autosomal dominant)
GPRg2
GPRg2KAL3
KAL3
PKR2
PKR2PK-R2
Prokineticin R2
prokineticin receptor 2
ProkineticinR2
PROKR2
Background
Corticotropin Releasing Factor Receptor 2 (CRHR2) expression has been reported in various regions of the brain, as well as in placenta, umbilical vein, heart, epididymis, gastrointestinal tract, adrenal, and skeletal muscle. It shows high-affinity CRF binding and also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. CRCH2 alpha is the dominant isoform and is expressed widely. CRCH2 beta is expressed in the hippocampus, septum, amygdala, heart, and skeletal muscle. CRHR2 gamma is brain-specific. ESTs have been isolated from brain libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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