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Pea3 Antibody [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 488

Order Details

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Pea3 Antibody [DyLight 488] Summary

Immunogen
Pea3 antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human Pea3. Amino Acid Squence: HSPTTRIKKEPQSPRTDPA
Specificity
At least three isoforms of Pea3 are known to exist. This antibody will only detect the two longest isoforms.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ETV4
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Pea3 Antibody [DyLight 488]

  • Adenovirus E1A enhancer-binding protein
  • E1A-FE1A enhancer binding protein
  • E1AFETS translocation variant 4
  • ets variant 4
  • ets variant gene 4 (E1A enhancer binding protein, E1AF)
  • ets variant gene 4 (E1A enhancer-binding protein, E1AF)
  • EWS protein/E1A enhancer binding protein chimera
  • PEA3
  • PEAS3
  • Polyomavirus enhancer activator 3 homolog
  • polyomavirus enhancer activator-3
  • Protein PEA3

Background

Pea3, also known as ETS translocation variant 4, is an approximately 54 kDa, 484 amino acid protein, which is involved in transcriptional activation of adenovirus E1A gene, and is regulated by ERBB2, STK11, PLAG1, CTNNB1. Studies about the Pea3 protein are being done on diseases such as ovaria, pancreatic, gastric, breast, and prostate cancers. As well as peripheral primitive neuroectodermal tumors, carcinoma, adenoma, ewings sarcoma, squamous cell carcinoma, and oral cancers. The Pea3 protein has shown interaction with Taf7, EP300, SRF, HOXD4, STK11, and involvement in the ErbB2-ErbB3 Heterodimer pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Pea3 Antibody (NBP2-81873G) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ETV4