Pea3 Antibody (3G9-1B9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Pea3, also known as ETS translocation variant 4, is an approximately 54 kDa, 484 amino acid protein, which is involved in transcriptional activation of adenovirus E1A gene, and is regulated by ERBB2, STK11, PLAG1, CTNNB1. Studies about the Pea3 protein are being done on diseases such as ovaria, pancreatic, gastric, breast, and prostate cancers. As well as peripheral primitive neuroectodermal tumors, carcinoma, adenoma, ewings sarcoma, squamous cell carcinoma, and oral cancers. The Pea3 protein has shown interaction with Taf7, EP300, SRF, HOXD4, STK11, and involvement in the ErbB2-ErbB3 Heterodimer pathway.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 application: WB.

Showing Publications 1 - 6 of 6.

Publications using H00002118-M01	Applications	Species
Irene C, Annalisa M, Chiara P et al. Identification and characterization of novel ETV4 splice variants in prostate cancer. Sci Rep. 2023-03-31 [PMID: 37002241]
Van den Eynden J, Umapathy G, Ashouri A et al. Phosphoproteome and gene expression profiling of ALK inhibition in neuroblastoma cell lines reveals conserved oncogenic pathways. Sci Signal. 2018-11-20 [PMID: 30459281]
Mesquita D, Barros-Silva JD, Santos J et al. Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts. Oncotarget 2015-03-10 [PMID: 25595908] (WB)	WB
Qi M, Liu Z, Shen C et al. Overexpression of ETV4 is associated with poor prognosis in prostate cancer: involvement of uPA/uPAR and MMPs. Tumour Biol 2015-05-01 [PMID: 25544710]
Pellecchia A, Pescucci C, De Lorenzo E et al. Overexpression of ETV4 is oncogenic in prostate cells through promotion of both cell proliferation and epithelial to mesenchymal transition. Oncogenesis. 2012-01-01 [PMID: 23552736]
Han B, Mehra R, Dhanasekaran SM et al. A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer. Cancer Res;68(18):7629-37. 2008-09-15 [PMID: 18794152]

Array H00002118-M01

• Pea3 Antibodies
• Pea3 Lysates
• Pea3 Protein