Pax2 Antibody (3C7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC/IF, Immunocytochemistry/ Immunofluorescence, WB.

Showing Publications 1 - 10 of 17. Show All 17 Publications. Collapse Publications.

Publications using H00005076-M01	Applications	Species
Wang X, Fan W, Xu Z et al. SOX2-positive retinal stem cells are identified in adult human pars plicata by single-cell transcriptomic analyses MedComm 2023-02-01 [PMID: 36582303] (Immunocytochemistry/ Immunofluorescence)	Immunocytochemistry/ Immunofluorescence
Yaqing W, Li W, Yaqiong G et al. Engineering stem cell-derived 3D brain organoids in a perfusable organ-on-a-chip system. RSC Adv. 2018-01-05 [PMID: 35540867]
Knoblich J, Lancester MA., et al. Three Dimensional Heterogeneously Differentiated Tissue Culture. United States Patent Application 2015-11-19
Shota O, Honoka I, Ayano S et al. Generation of two induced pluripotent stem cell lines from individuals without auditory disorders. Stem Cell Res. 2023-01-04 [PMID: 36630839]
Kazuhiko B, Makoto K, Haruki N et al. Upregulation of the hypothalamo-neurohypophysial system and activation of vasopressin neurones attenuates hyperalgesia in a neuropathic pain model rat. Sci Rep. 2022-08-05 [PMID: 35906406]
Kangli C, Yaqing W, Yujuan Z et al. Neurodevelopmental impairment induced by prenatal valproic acid exposure shown with the human cortical organoid-on-a-chip model. Microsyst Nanoeng. 2020-07-13 [PMID: 34567661]
Yasuhito M, Yoichi U, Akinori S et al. Analysis of the proportion and neuronal activity of excitatory and inhibitory neurons in the rat dorsal spinal cord after peripheral nerve injury. Neurosci Lett. 2021-02-15 [PMID: 33600905]
May T, Joao B, Katherine H et al. Ablation of spinal cord estrogen receptor ?-expressing interneurons reduces chemically-induced modalities of pain and itch. J Comp Neurol. 2020-01-06 [PMID: 31872868]
Wang Y, Wang L, Zhu Y, Qin J. Human brain organoid-on-a-chip to model prenatal nicotine exposure. Lab Chip 2018-03-13 [PMID: 29437173] (Human)		Human
Patel D, Shimomura A, Majumdar S et al. The histone demethylase LSD1 regulates inner ear progenitor differentiation through interactions with Pax2 and the NuRD repressor complex. PLoS One 2018-01-25 [PMID: 29370269] (WB, Mouse)	WB	Mouse
Zhu Y, Wang L, Yin F et al. Probing impaired neurogenesis in human brain organoids exposed to alcohol. Integr Biol (Camb) 2017-12-11 [PMID: 29168871]
Zhu Y, Wang L, Yu H et al. In situ generation of human brain organoids on a micropillar array. Lab Chip 2017-07-28 [PMID: 28752164]
Vinci L, Ravarino A, Fanos V et al. Immunohistochemical markers of neural progenitor cells in the early embryonic human cerebral cortex. Eur J Histochem 2016-02-01 [PMID: 26972711]
Lancaster MA, Renner M, Martin CA et al. Cerebral organoids model human brain development and microcephaly. Nature 2013-09-19 [PMID: 23995685] (ICC/IF)	ICC/IF
Koehler KR, Mikosz AM, Molosh AI et al. Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture. Nature. 2013-07-10 [PMID: 23842490]
Bains OS, Grigliatti TA, Reid RE, Riggs KW. Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin. J Pharmacol Exp Ther. 2010-09-13 [PMID: 20837989]
Muguruma K, Nishiyama A, Ono Y et al. Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells. Nat Neurosci. 2010-09-12 [PMID: 20835252]
Show All 17 Publications. Collapse Publications.

Array H00005076-M01

• Pax2 Antibodies
• Pax2 Lysates
• Pax2 Proteins