Reactivity | Hu, Mu, Rt, Po, Ch, Ze, PmSpecies Glossary |
Applications | WB, Simple Western, ICC/IF, IHC, WB |
Clonality | Polyclonal |
Host | Rabbit |
Conjugate | DyLight 650 |
Immunogen | A synthetic peptide made to an internal region within residues 500-600 of human OPA1. [Swiss-Prot: O60313] |
Localization | Mitochondrion; mitochondrial inner membrane; single-pass membrane protein. Mitochondrion; mitochondrial intermembrane space. |
Predicted Species | Primate (100%). Backed by our 100% Guarantee. |
Isotype | IgG |
Clonality | Polyclonal |
Host | Rabbit |
Gene | OPA1 |
Purity | Immunogen affinity purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
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Publications |
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Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Immunogen affinity purified |
Publication using NB110-55290C | Applications | Species |
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Gomez-Valades Ag, Pozo M, Varela L Et Al. Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis Cell metabolism 2021-07-27 [PMID: 34343501] |
Secondary Antibodies |
Isotype Controls |
Research Areas for OPA1 Antibody (NB110-55290C)Find related products by research area.
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Losing memory: Toxicity from mutant APP and amyloid beta explain the hippocampal neuronal damage in Alzheimer's disease By Jamshed Arslan Pharm.D. Alzheimer's disease (AD) is an irreversible brain disorder that destroys memory and thinking skills. The telltale signs of AD brains are extracellular deposits of amy... Read full blog post. |
BNIP3 - a regulator of mitochondrial autophagy and cell death Bcl-2 nineteen-kilodalton interacting protein 3 (BNIP3) is a pro-apoptotic BH3-only protein. BNIP3 localizes to the mitochondrial membrane where it plays a key role in mitochondrial autophagy and cell death pathways. Similar to other Bcl-2 family m... Read full blog post. |
Understanding OPA1 and Mitochondrial Function OPA1 belongs to the Dynamin large GTPase protein family. OPA1 exists as a single-pass membrane protein localized in the mitochondrial inner membrane and also as a soluble form in the mitochondrial intermembrane space. There, it is a key player in fusi... Read full blog post. |
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Gene Symbol | OPA1 |