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NTAL Antibody (NAP-07) [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, ICC/IF, IP, CyTOF-ready
Clone
NAP-07
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

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NTAL Antibody (NAP-07) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Recombinant cytoplasmic domain (amino acids 91-244) of Human NTAL.
Specificity
The antibody NAP-07 reacts with Non-T cell activation linker (NTAL), also known as LAB (linker of activated B cells), a 25 - 30 kDa transmembrane adaptor protein present in membrane microdomains (rafts) of B lymphocytes, NK cells and myeloid cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LAT2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow (Intracellular)
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for NTAL Antibody (NAP-07) [CoraFluor™ 1]

  • LAB
  • LABWilliams-Beuren syndrome chromosomal region 15 protein
  • Linker for activation of B-cells
  • linker for activation of T cells family, member 2
  • linker for activation of T-cells family member 2
  • Membrane-associated adapter molecule
  • Non-T-cell activation linker
  • NTAL
  • NTALWilliams-Beuren syndrome chromosomal region 5 protein
  • WBS15
  • WBSCR15
  • WBSCR5
  • WBSCR5HSPC046
  • Williams-Beuren syndrome chromosome region 5
  • WSCR5

Background

Non T cell activation linker (NTAL), also known as LAB (linker of activated B cells),is a 30 kDa transmembrane adaptor protein present in membrane microdomains (rafts) of B cells, NK cells and myeloid cells. It is involved in immunoreceptor signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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ICC/IF Video Protocol

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Bioinformatics

Gene Symbol LAT2