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Nogo Antibody (NG-101)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
NG-101
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28324AF350
Alexa Fluor 405
NBP3-28324AF405
Alexa Fluor 488
NBP3-28324AF488
Alexa Fluor 532
NBP3-28324AF532
Alexa Fluor 594
NBP3-28324AF594
Alexa Fluor 647
NBP3-28324AF647
Alexa Fluor 700
NBP3-28324AF700
Alexa Fluor 750
NBP3-28324AF750
Allophycocyanin
NBP3-28324APC
Biotin
NBP3-28324B
CoraFluor 1
NBP3-28324CL1
DyLight 350
NBP3-28324UV
DyLight 405
NBP3-28324V
DyLight 488
NBP3-28324G
DyLight 550
NBP3-28324R
DyLight 594
NBP3-28324DL594
DyLight 650
NBP3-28324C
DyLight 680
NBP3-28324FR
DyLight 755
NBP3-28324IR
FITC
NBP3-28324F
HRP
NBP3-28324H
Janelia Fluor 525
NBP3-28324JF525
Janelia Fluor 549
NBP3-28324JF549
Janelia Fluor 585
NBP3-28324JF585
Janelia Fluor 635
NBP3-28324JF635
Janelia Fluor 646
NBP3-28324JF646
Janelia Fluor 669
NBP3-28324JF669
PE
NBP3-28324PE
PerCP
NBP3-28324PCP
mFluor Violet 450 SE
NBP3-28324MFV450
mFluor Violet 500 SE
NBP3-28324MFV500
mFluor Violet 610 SE
NBP3-28324MFV610
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Nogo Antibody (NG-101) Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
RTN4 / NOGO
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
RTN4
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at -20C in powder form. Store at -80C once reconstituted.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Nogo Antibody (NG-101)

  • ASY
  • foocen
  • Human NogoA
  • KIAA0886
  • My043 protein
  • Nbla00271
  • Nbla10545
  • neurite growth inhibitor 220
  • Neurite outgrowth inhibitor
  • Neuroendocrine-specific protein C homolog
  • Neuroendocrine-specific protein
  • NI220/250
  • Nogo protein
  • NOGO-A
  • Nogo-B
  • NOGOC
  • Nogo-C
  • NOGORTN4-B1
  • NSP
  • NSP-CL
  • reticulon 4
  • reticulon 5
  • reticulon-4
  • reticulon-5
  • RTN4-A
  • RTN4-B2
  • RTN4-C
  • RTN-x

Background

Neurite Outgrowth Inhibitor (NOGO) is a myelin associated neurite growth inhibitor found in oligodendrocyte and central nervous system (CNS) myelin membranes of the adult CNS. NOGO plays a role in blocking axonal regeneration in the CNS of higher vertebrates. At least 6 isoforms have been observed arising from alternative splicing. NOGO-A (Isoform 1) is specifically expressed in brain and testes and weakly expressed in heart and skeletal muscle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Nogo Antibody
(NG-101)
NBP3-28324
Nogo Antibody (NG-101)
Species: Hu
Applications: ELISA, Flow, Func

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Isotype Controls

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Nogo: A Promising Target for New Gene Therapies
Nogo is a neurite outgrowth inhibitor protein that plays an important role during central nervous system (CNS) development as well as in endoplasmic reticulum signaling regulation. Studies using Nogo antibodies have revealed Nogo proteins regulate ...  Read full blog post.
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Bioinformatics

Gene Symbol RTN4
Uniprot