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MYO3A Antibody (8H2)

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Western Blot: MYO3A Antibody (8H2) [H00053904-M08] - Analysis of MYO3A expression in Hela S3 NE (Cat # L013V3).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
8H2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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MYO3A Antibody (8H2) Summary

Immunogen
MYO3A (NP_059129, 1400 a.a. ~ 1490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. HEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSEEYFILQKKLNEMILSQQLKSLYLGVSHHKPINRRVSSQQCLSGVCKGEEPKIL
Specificity
MYO3A (8H2)
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
MYO3A
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MYO3A Antibody (8H2)

  • deafness, autosomal recessive 30
  • DFNB30
  • EC 2.7.11
  • EC 2.7.11.1
  • myosin IIIA
  • myosin-IIIa

Background

The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional MYO3A Products

Array H00053904-M08

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Bioinformatics

Gene Symbol MYO3A
Entrez
OMIM
Uniprot