Mouse IFN-beta ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 30. Show All 30 Publications. Collapse Publications.

Publications using 42400-1	Applications	Species
F Raya Tonet, P Clua, K Fukuyama, G Marcial, J Sacur, G Marranzino, M Tomokiyo, G Vizoso-Pin, A Garcia-Can, S Kurata, H Kitazawa, J Villena The Ability of Postimmunobiotics from L. rhamnosus CRL1505 to Protect against Respiratory Syncytial Virus and Pneumococcal Super-Infection Is a Strain-Dependent Characteristic Microorganisms, 2022-11-03;10(11):. 2022-11-03 [PMID: 36363777] (Mouse)		Mouse
G Wan, Y An, J Tao, Y Wang, Q Zhou, R Yang, Q Liang MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-&kappaB pathway Biosci. Rep., 2020-03-27;40(3):. 2020-03-27 [PMID: 32096822] (Mouse)		Mouse
JH Kim, JE Yoon, C Nikapitiya, TH Kim, MB Uddin, HC Lee, YH Kim, JH Hwang, K Chathurang, WAG Chathurang, HS Choi, CJ Kim, JU Jung, CH Lee, JS Lee Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus Cell Rep, 2019-05-14;27(7):2105-2118.e5. 2019-05-14 [PMID: 31091449] (Mouse)		Mouse
K Wang, H Ma, H Liu, W Ye, Z Li, L Cheng, L Zhang, Y Lei, L Shen, F Zhang The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses Cell Rep, 2019-05-14;27(7):2075-2091.e5. 2019-05-14 [PMID: 31091447] (Human, Mouse)		Human, Mouse
P Xia, S Wang, B Ye, Y Du, C Li, Z Xiong, Y Qu, Z Fan A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion Immunity, 2018-04-03;0(0):. 2018-04-03 [PMID: 29625897] (Mouse)		Mouse
CH Jin, HC Park, Y So, B Nam, SN Han, JB Kim Comparison of the Anti-Inflammatory Activities of Supercritical Carbon Dioxide versus Ethanol Extracts from Leaves of Perilla frutescens Britt. Radiation Mutant Molecules, 2017-02-17;22(2):. 2017-02-17 [PMID: 28218690] (Mouse)		Mouse
The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination Nat. Immunol, 2016-12-19;0(0):. 2016-12-19 [PMID: 27992402] (Mouse)		Mouse
Rosmarinic Acid Methyl Ester Inhibits LPS-Induced NO Production via Suppression of MyD88- Dependent and -Independent Pathways and Induction of HO-1 in RAW 264.7 Cells Molecules, 2016-08-18;21(8):. 2016-08-18 [PMID: 27548124] (Mouse)		Mouse
IFN-? Production During the dsRNA Response in Hepatocytes Involves Coordinated and Feed Forward Signaling Through TLR3, PKR, iNOS and Src J Biol Chem, 2016-05-17;0(0):. 2016-05-17 [PMID: 27226571] (Mouse)		Mouse
Liu L, Nishikawa T, Kaneda Y An RNA Molecule Derived From Sendai Virus DI Particles Induces Antitumor Immunity and Cancer Cell-selective Apoptosis. Mol Ther, 2015-11-09;24(1):135-45. 2015-11-09 [PMID: 26548591] (Mouse)		Mouse
Zhu W, Zhao S, Liu Z, Cheng L, Wang Q, Yan K, Chen Q, Wu H, Han D Pattern recognition receptor-initiated innate antiviral responses in mouse epididymal epithelial cells. J Immunol, 2015-04-03;194(10):4825-35. 2015-04-03 [PMID: 25840915] (Mouse)		Mouse
Wang P, Zhao W, Zhao K, Zhang L, Gao C TRIM26 negatively regulates interferon-beta production and antiviral response through polyubiquitination and degradation of nuclear IRF3. PLoS Pathog, 2015-03-12;11(3):e1004726. 2015-03-12 [PMID: 25763818] (Mouse)		Mouse
Park , Sun Hong, Baek , Seung-Il, Yun , Jieun, Lee , Seungmin, Yoon , Da Young, Jung , Jae-Kyun, Jung , Sang-Hun, Hwang , Bang Yeo, Hong , Jin Tae, Han , Sang-Bae, Kim , Youngsoo IRAK4 as a molecular target in the amelioration of innate immunity-related endotoxic shock and acute liver injury by chlorogenic acid. J Immunol, 2014-12-29;194(3):1122-30. 2014-12-29 [PMID: 25548221] (Mouse)		Mouse
Ranjan P, Singh N, Kumar A, Neerincx A, Kremmer E, Cao W, Davis W, Katz J, Gangappa S, Lin R, Kufer T, Sambhara S NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection. Eur J Immunol, 2014-12-23;45(3):758-72. 2014-12-23 [PMID: 25404059] (Mouse)		Mouse
Zaru R, Edgar A, Hanauer A, Watts C Structural and functional basis for p38-MK2-activated Rsk signaling in toll-like receptor-stimulated dendritic cells. Mol Cell Biol, 2014-10-20;35(1):132-40. 2014-10-20 [PMID: 25332232] (Mouse)		Mouse
Desch , A Nicole, Gibbings , Sophie L, Clambey , Eric T, Janssen , William, Slansky , Jill E, Kedl , Ross M, Henson , Peter M, Jakubzick , Claudia Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction. Nat Commun, 2014-08-19;5(0):4674. 2014-08-19 [PMID: 25135627] (Mouse)		Mouse
Kanagavelu S, Flores C, Termini J, Riveron R, Romero L, Chung K, Ruiz J, Hyun J, Yuan X, Dagvadorj J, Fukata M TIR-domain-containing adapter-inducing interferon-beta (TRIF) regulates Th17-mediated intestinal immunopathology in colitis. Mucosal Immunol, 2014-07-30;8(2):296-306. 2014-07-30 [PMID: 25073675] (Mouse)		Mouse
Dulek D, Newcomb D, Toki S, Goliniewska K, Cephus J, Reiss S, Bates J, Crowe J, Boyd K, Moore M, Zhou W, Peebles R STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge. J Virol, 2014-06-11;88(17):9655-72. 2014-06-11 [PMID: 24920804] (Mouse)		Mouse
Bosmann M, Strobl B, Kichler N, Rigler D, Grailer J, Pache F, Murray P, Muller M, Ward P Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27. J Leukoc Biol, 2014-03-06;96(1):123-31. 2014-03-06 [PMID: 24604832] (Mouse)		Mouse
Cai , Xinming, Xu , Yongyao, Kim , You-Me, Loureiro , Joseph, Huang , Qian PIKfyve, a class III lipid kinase, is required for TLR-induced type I IFN production via modulation of ATF3. J Immunol, 2014-03-05;192(7):3383-9. 2014-03-05 [PMID: 24600036] (Mouse)		Mouse
Jayaraman A, Jackson D, Message S, Pearson R, Aniscenko J, Caramori G, Mallia P, Papi A, Shamji B, Edwards M, Westwick J, Hansel T, Stanciu L, Johnston S, Bartlett N IL-15 complexes induce NK- and T-cell responses independent of type I IFN signaling during rhinovirus infection. Mucosal Immunol, 2014-01-29;7(5):1151-64. 2014-01-29 [PMID: 24472849] (Mouse)		Mouse
Zhang W, Zhou Q, Xu W, Cai Y, Yin Z, Gao X, Xiong S DNA-dependent activator of interferon-regulatory factors (DAI) promotes lupus nephritis by activating the calcium pathway. J Biol Chem, 2013-04-03;288(19):13534-50. 2013-04-03 [PMID: 23553627] (Mouse)		Mouse
Ferguson , Brian J, Mansur , Daniel S, Peters , Nicholas, Ren , Hongwei, Smith , Geoffrey DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. Elife, 2012-12-18;1(0):e00047. 2012-12-18 [PMID: 23251783] (Mouse)		Mouse
Chen K, Chang C, Huang C, Lin C, Lin W, Lo Y, Yang C, Hsing E, Chen L, Shih S, Shiau A, Lei H, Tan T, Ling P TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity. J Biol Chem, 2012-07-25;287(38):32216-21. 2012-07-25 [PMID: 22833682] (Mouse)		Mouse
Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis. J. Immunol., 2010-11-22;186(1):556-62. 2010-11-22 [PMID: 21098223] (Mouse)		Mouse
Guerra S, Gonzalez JM, Climent N, Reyburn H, Lopez-Fernandez LA, Najera JL, Gomez CE, Garcia F, Gatell JM, Gallart T, Esteban M Selective induction of host genes by MVA-B, a candidate vaccine against HIV/AIDS. J. Virol., 2010-06-09;84(16):8141-52. 2010-06-09 [PMID: 20534857] (Mouse)		Mouse
Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway. J. Clin. Invest., 2010-04-12;120(5):1645-62. 2010-04-12 [PMID: 20389019] (Mouse)		Mouse
Zurney J, Howard KE, Sherry B Basal expression levels of IFNAR and Jak-STAT components are determinants of cell-type-specific differences in cardiac antiviral responses. J. Virol., 2007-10-17;81(24):13668-80. 2007-10-17 [PMID: 17942530] (Mouse)		Mouse
Zetterstrom CK, Jiang W, Wahamaa H, Ostberg T, Aveberger AC, Schierbeck H, Lotze MT, Andersson U, Pisetsky DS, Erlandsson Harris H Pivotal advance: inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate. J. Leukoc. Biol., 2007-10-03;83(1):31-8. 2007-10-03 [PMID: 17913975] (Mouse)		Mouse
Qin L, Greenland JR, Moriya C Effects of type I interferons on the adjuvant properties of plasmid granulocyte-macrophage colony-stimulating factor in vivo. J. Virol., 2007-07-25;81(19):10606-13. 2007-07-25 [PMID: 17652387] (Mouse)		Mouse
Show All 30 Publications. Collapse Publications.

Array 42400-1

• IFN-beta Antibodies
• IFN-beta ELISA Kits
• IFN-beta Lysate
• IFN-beta Proteins
• IFN-beta Proteins and Enzymes
• IFN-beta ELISAs