Western Blot: MCT2 Antibody [NBP1-87846] - Analysis in control (vector only transfected HEK293T lysate) and SLC16A7 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T ...read more
Immunohistochemistry-Paraffin: MCT2 Antibody [NBP1-87846] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neuronal cells.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for MCT2 Antibody
MCT 2
MCT2
MCT2solute carrier family 16 (monocarboxylic acid transporters), member 7
monocarboxylate transporter 2
SLC16A7
Solute carrier family 16 member 7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
Background
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family 16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. MCT2 is a high affinity transporter that catalyzes the rapid transport of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate across the plasma membrane.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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