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Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody [Alexa Fluor® 350]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ChIP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Alexa Fluor 350

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Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody [Alexa Fluor® 350] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 475 and 525 of human Jumonji Domain Containing 2C using the numbering given in entry NP_055876.2
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KDM4C
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Chromatin Immunoprecipitation (ChIP)
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:33441614)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody [Alexa Fluor® 350]

  • EC 1.14.11
  • EC 1.14.11.-
  • GASC-1 protein
  • GASC1
  • GASC1JmjC domain-containing histone demethylation protein 3C
  • Gene amplified in squamous cell carcinoma 1 protein
  • JHDM3C
  • JMJD2C
  • JMJD2CbA146B14.1
  • jumonji domain containing 2C
  • Jumonji domain-containing protein 2C
  • KDM4C
  • KIAA0780FLJ25949
  • Lysine (K)specific Demethylase 4C
  • Lysine (K)-specific Demethylase 4C
  • lysine-specific demethylase 4C

Background

JMJD2C is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KDM4C