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Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9)

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Western Blot: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY JMJD2C(Right lane) cDNA for 48 hrs ...read more
Immunocytochemistry/ Immunofluorescence: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY JMJD2C.
Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of paraffin-embedded pancreas tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of paraffin-embedded Carcinoma of prostate tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of paraffin-embedded Carcinoma of thyroid tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of paraffin-embedded colon tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of paraffin-embedded endometrium tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of paraffin-embedded Ovary tissue using anti-JMJD2C mouse monoclonal antibody.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
OTI5B9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

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Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) Summary

Immunogen
Full-length protein expressed in 293T cell transfected with human KDM4C expression vector
Specificity
This antibody is specific for Homo sapiens lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KDM4C
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Immunohistochemistry 1:50
  • Immunohistochemistry-Paraffin 1:50
  • Western Blot 1:2000
Theoretical MW
120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9)

  • EC 1.14.11
  • EC 1.14.11.-
  • GASC-1 protein
  • GASC1
  • GASC1JmjC domain-containing histone demethylation protein 3C
  • Gene amplified in squamous cell carcinoma 1 protein
  • JHDM3C
  • JMJD2C
  • JMJD2CbA146B14.1
  • jumonji domain containing 2C
  • Jumonji domain-containing protein 2C
  • KDM4C
  • KIAA0780FLJ25949
  • Lysine (K)specific Demethylase 4C
  • Lysine (K)-specific Demethylase 4C
  • lysine-specific demethylase 4C

Background

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KDM4C
Entrez