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LRP2 Antibody

Images

 
Orthogonal Strategies: Immunohistochemistry-Paraffin: LRP2 Antibody [NBP1-85292] - Staining in human kidney and skeletal muscle tissues.. Corresponding LRP2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: LRP2 Antibody [NBP1-85292] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: LRP2 Antibody [NBP1-85292] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: LRP2 Antibody [NBP1-85292] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: LRP2 Antibody [NBP1-85292] - Staining of human thyroid gland shows moderate to strong cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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LRP2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: GFTSMSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LRP2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
LRP2 Protein (NBP1-85292PEP)
Publications
Read Publication using NBP1-85292.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for LRP2 Antibody

  • calcium sensor protein
  • DBS
  • DBSlow-density lipoprotein receptor-related protein 2
  • EC 1.1.2.3
  • EC 3.4.21.9
  • Glycoprotein 330
  • gp330
  • Heymann nephritis antigen homolog
  • low density lipoprotein receptor-related protein 2
  • LRP2
  • LRP-2
  • Megalin

Background

Megalin/gp330, an approx. 600 kDa transmembrane glycoprotein is a large cell surface receptor that mediates the binding and internalization of a number of structurally and functionally distinct ligands from the lipoprotein and protease inhibitor families.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for LRP2 Antibody (NBP1-85292)(1)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol LRP2
Entrez
Uniprot