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Lipoprotein Lipase/LPL Antibody (10E10P9)

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Western Blot: Lipoprotein Lipase/LPL Antibody (10E10P9) [NBP3-16334] - Western blot analysis of extracts of Human plasma, using Lipoprotein Lipase/LPL (LPL) Rabbit mAb (NBP3-16334) at 1:1000 dilution. Secondary ...read more
Western Blot: Lipoprotein Lipase/LPL Antibody (10E10P9) [NBP3-16334] - Western blot analysis of extracts of Mouse liver, using Lipoprotein Lipase/LPL (LPL) Rabbit mAb (NBP3-16334) at 1:1000 dilution. Secondary antibody: ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA
Clone
10E10P9
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Lipoprotein Lipase/LPL Antibody (10E10P9) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 376-475 of human Lipoprotein Lipase/LPL (P06858). IPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
LPL
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500 - 1:2000
Theoretical MW
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 0.05% BSA, 50% glycerol, pH7.3
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Lipoprotein Lipase/LPL Antibody (10E10P9)

  • EC 3.1.1
  • HDLCQ11
  • LIPD
  • LIPDEC 3.1.1.34
  • Lipoprotein Lipase
  • LPL

Background

LPL, also known as Lipoprotein lipase, is a 475 amino acid that is 53 kDa, is a vascular lipase, but not synthesized in endothelial cells. It is anchored to the capillary endothelium by proteoglycans and acts as a catalyzer of triglycerides hydrolysis to release free fatty acids into the circulation and initiates the processing of triglyceride-rich lipoproteins such as chylomicrons and VLDL. It is being studied for its involvement in 150+ diseases and disorders including high density lipoprotein cholesterol level qtl 11, hyperlipoproteinemia, lipoprotein lipase deficiency, familial lipoprotein lipase deficiency, hyperlipoproteinemia type v, lipase deficiency combined, hyperlipoproteinemia type iii, glycogen storage disease, hyperlipidemia, hypertriglyceridemia, glucose intolerance, cetp deficiency, hypertension, fatty liver, nephrotic syndrome, kidney failure, and myocardial infarction. This protein has been shown to interact with 50 proteins including COPS6, PTPN4, RPL18A, ASCC2, KIAA1377 in developmental biology, transcriptional regulation of white adipocyte differentiation, lipid digestion, mobilization, and transport, metabolism, lipoprotein metabolism, glycerolipid metabolism, PPAR signaling pathway, and Alzheimer's disease pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol LPL