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GCN2 Antibody [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 549

Order Details

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GCN2 Antibody [Janelia Fluor® 549] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 1 and 50 of human GCN2 (eIF2AK4, eukaryotic translation initiation factor 2 alpha kinase 4) using the numbering given in entry NP_001013725.2 (GeneID 440275).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EIF2AK4
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for GCN2 Antibody [Janelia Fluor® 549]

  • EIF2AK4
  • eukaryotic translation initiation factor 2 alpha kinase 4
  • eukaryotic translation initiation factor 2-alpha kinase 4
  • GCN2
  • GCN2GCN2 eIF2alpha kinase
  • GCN2-like protein
  • KIAA1338EC 2.7.11.1

Background

GCN2 is a sensor of amino acid deprivation. GCN2 was recently found to regulate lipid metabolism during leucine deprivation in addition to regulating amino acid metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

Additional GCN2 Products

Array NB100-1593JF549

Research Areas for GCN2 Antibody (NB100-1593JF549)

Find related products by research area.

Blogs on GCN2.

eIF2alpha - a regulator of global translation in response to cellular stress
Eukaryotic initiation factor 2 (eIF2) regulates global protein translation by binding to Met-tRNA and the 40S ribosome to form the pre-initiation complex. eIF2 is a heterotrimer consisting of alpha, beta, and gamma subunits. The 36kDA eIF2a subuni...  Read full blog post.

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Bioinformatics

Gene Symbol EIF2AK4