FKBP12 Antibody (1E5-A12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels including the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. There is evidence of multiple alternatively spliced transcript variants for this gene, but the full length nature of some variants has not been determined.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 2 of 2.

Publications using H00002280-M01	Applications	Species
Chiurchiu V, Rapino C, Talamonti E et al. Anandamide Suppresses Proinflammatory T Cell Responses In Vitro through Type-1 Cannabinoid Receptor-Mediated mTOR Inhibition in Human Keratinocytes. J Immunol 2016-11-01 [PMID: 27694494] (Human)		Human
Sitaraman K, Chatterjee DK. Protein-protein interactions: an application of tus-ter mediated protein microarray system. Methods Mol Biol. 2011-03-03 [PMID: 21370066]

Array H00002280-M01

• FKBP12 Antibodies
• FKBP12 ELISA Kits
• FKBP12 Lysates
• FKBP12 Proteins
• FKBP12 Proteins and Enzyme