FGFR1OP Antibody (2B1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 3 applications: Block/Neutralize, ICC/IF, Immunocytochemistry/ Immunofluorescence.

Showing Publications 1 - 10 of 18. Show All 18 Publications. Collapse Publications.

Publications using H00011116-M01	Applications	Species
Lena B, Anca M, Camille B et al. LRP2 contributes to planar cell polarity-dependent coordination of motile cilia function. Cell Tissue Res. 2023-02-11 [PMID: 36764939]
Tomoharu K, Roy N, Keene A et al. Myristoylated Neuronal Calcium Sensor-1 captures the ciliary vesicle at distal appendages. bioRxiv. 2023-01-10 [PMID: 36712037]
Tomoharu K, Julia L, Saxton F et al. A hierarchical pathway for assembly of the distal appendages that organize primary cilia. bioRxiv. 2023-01-10 [PMID: 36711481]
G Ortiz-Álva, A Fortoul, A Srivastava, MX Moreau, B Bouloudi, C Mailhes-Ha, N Delgehyr, M Faucourt, M Bahin, C Blugeon, M Breau, V Géli, F Causeret, A Meunier, N Spassky p53/p21 pathway activation contributes to the ependymal fate decision downstream of GemC1 Cell Reports, 2022-12-13;41(11):111810. 2022-12-13 [PMID: 36516767]
Adelaida P, Keren H, Ann Y et al. Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging. Nat Commun. 2022-03-17 [PMID: 35301320]
Sayaka F, Hantian Q, Shohei N et al. ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane. Biol Open. 2021-09-28 [PMID: 34447983]
Wu CT, Hilgendorf KI, Bevacqua RJ et al. Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion Genes & Development 2021-09-01 [PMID: 34385262] (Block/Neutralize, Immunocytochemistry/ Immunofluorescence)	Block/Neutralize, Immunocytochemistry/ Immunofluorescence
Gon�alves AB, Hasselbalch SK, Joensen BB et al. CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels eLife 2021-07-14 [PMID: 34259627]
Takuya K, Yamato I, Tomoaki H et al. Cooperation of the IFT-A complex with the IFT-B complex is required for ciliary retrograde protein trafficking and GPCR import. Mol Biol Cell. 2020-11-11 [PMID: 33175651]
Racha C, Adham S, Xavier P et al. A Dual Protein-mRNA Localization Screen Reveals Compartmentalized Translation and Widespread Co-translational RNA Targeting. Dev Cell. 2020-08-04 [PMID: 32783880]
Martina B, Nicolas K, Serena B et al. mTOR and S6K1 Drive Polycystic Kidney by the Control of Afadin-dependent Oriented Cell Division. Nat Commun. 2020-01-24 [PMID: 32581239]
Hilgendorf KI, Johnson CT, Mezger A et al. Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis Cell 2019-11-27 [PMID: 31761534]
Ortiz-Alvarez G, Daclin M, Shihavuddin A et al. Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members. Neuron. 2019-02-26 [PMID: 30824354]
Mahuzier A, Shihavuddin A, Fournier C et al. Ependymal cilia beating induces an actin network to protect centrioles against shear stress. Nat Commun 2018-06-11 [PMID: 29891944]
kanie T, Abbott kL, MooneY NA et al. The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Dev. Cell. 2017-07-10 [PMID: 28625565] (ICC/IF, Mouse)	ICC/IF	Mouse
Mazo G, Soplop N, Wang WJ et al. Spatial Control of Primary Ciliogenesis by Subdistal Appendages Alters Sensation-Associated Properties of Cilia Developmental Cell 2016-11-01 [PMID: 27818179]
Boutin C, Labedan P, Dimidschstein J et al. A dual role for planar cell polarity genes in ciliated cells. Proc Natl Acad Sci U S A. 2014-07-14 [PMID: 25024228]
Mano Y, Takahashi K, Ishikawa N et al. Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer. Cancer Sci 2007-09-20 [PMID: 17888034]
Show All 18 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: PRAVEEN BALLAB	IHC-Fr	new zealand rabbit and Rabbit	07/01/2020	View Summary Application Immunohistochemistry-Frozen Sample Tested Rabbit frozen 4% paraformalehyde fixed brain sections Species new zealand rabbit and Rabbit Lot N/A

Array H00011116-M01

• FGFR1OP Antibodies
• FGFR1OP Lysate
• FGFR1OP Proteins