Recombinant Human eIF4E His Protein

EIF4E, a member of eukaryotic initiation factor 4 families, modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. This protein recognizes and binds to the 7 methyl GTP cap structure of eukaryotic mRNAs, thereby mediating the initiation of translation. It facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Recombinant human EIF4E protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 application: Biacore Binding Assay.

Showing Publication 1 - 1 of 1.

Publication using NBP1-45314	Applications	Species
Chen X, Huang J, Yu C et al. A noncanonical function of EIF4E limits ALDH1B1 activity and increases susceptibility to ferroptosis Nature communications 2022-10-23 [PMID: 36274088] (Biacore Binding Assay)	Biacore Binding Assay

Array NBP1-45314

• eIF4E Antibodies
• eIF4E Lysate
• eIF4E Proteins