Reactivity | Hu, Mu, Rt, Ca, ChSpecies Glossary |
Applications | WB, ELISA, ICC/IF, B/N, SPR |
Clone | EDAR12 |
Clonality | Monoclonal |
Host | Rabbit |
Conjugate | Janelia Fluor 585 |
Additional Information | Recombinant Monoclonal Antibody |
Immunogen | EDAR12 was prepared by immunixzing female OVE1B mice (with the Edar gene deleted) subcutaneously with mouse EDAR-Fc and positive hybridoma clones were screened for binding mEDAR by ELISA. |
Specificity | EDAR12 recognises and binds to CRD1 of the extracellular domain of mouse EDAR. EDAR3 cross-reacts with EDAR derived from human, dog, rat and chicken when EDAR is fused to the glycosylphosphatidylinositol anchor of TRAILR3. EDAR is the receptor for the TNF family ligand EDA1, which is a type II transmembrane protein possessing a collagen-like domain and a C-terminal TNF-homology domain. EDAR is important for the correct development of skin appendages including hair, teeth and eccrine sweat glands. LoF mutations in the Eda gene is known to cause XLHED (X-linked hypohidrotic ectodermal dysplasia), and results in abnormal development. |
Isotype | IgG Kappa |
Clonality | Monoclonal |
Host | Rabbit |
Gene | EDAR |
Purity | Protein A purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Protein A purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for EDAR Antibody (NBP2-81103JF585)Find related products by research area.
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Gene Symbol | EDAR |