Dopamine beta-Hydroxylase Antibody

The production of neurotransmitters is controlled by environmental stimuli, which send signals through second messengers and protein kinase pathways. Regulation of gene expression of dopamine beta hydroxylase and tyrosine hydroxylase, two of the catecholamine biosynthetic enzymes, by cyclic AMP, diacyl glycerol, and Ca2+ leads to increased neurotransmitter biosynthesis. Dopamine beta-hydroxylase catalyzes the conversion of dopamine to noradrenaline and is expressed selectively in noradrenergic and adrenergic neurons in the nervous system. The disruption of the DBH gene is thought to cause changes in development and behavior in certain models. Both DBH and the multiple regulatory pathways of DBH are of increasing research in many neurological diseases.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publication 1 - 1 of 1.

Publication using NB300-112	Applications	Species
Li H, Ham A, Ma TC et al. Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations Autophagy 2019-01-01 [PMID: 30160596] (WB, Human)	WB	Human

Array NB300-112

• Dopamine beta-Hydroxylase Antibodies
• Dopamine beta-Hydroxylase ELISA Kits
• Dopamine beta-Hydroxylase Lysate
• Dopamine beta-Hydroxylase Proteins
• Dopamine beta-Hydroxylase Proteins and Enzyme