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DLEC/CLEC4C/BDCA-2 Antibody (CLEC4C/3400)

Images

 
Formalin-fixed, paraffin-embedded human placenta stained with CD303 / CLEC4C Mouse Monoclonal Antibody (CLEC4C/3400). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
Analysis of Protein Array containing more than 19,000 full-length human proteins using CD303 / CLEC4C Mouse Monoclonal Antibody (CLEC4C/3400).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
CLEC4C/3400
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

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DLEC/CLEC4C/BDCA-2 Antibody (CLEC4C/3400) Summary

Description
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.
Immunogen
Recombinant fragment (around aa1-250) of human DLEC/CLEC4C/BDCA-2 protein (exact sequence is proprietary)
Localization
Membrane
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CLEC4C
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1-2ug/ml for 30 minutes at RT
Application Notes
Immunohistochemistry-Paraffin 1-2ug/ml for 30 minutes at RT. Optimal dilution for a specific application should be determined.. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Alternate Names for DLEC/CLEC4C/BDCA-2 Antibody (CLEC4C/3400)

  • BDCA2
  • BDCA-2
  • BDCA2MGC125791
  • blood dendritic cell antigen 2 protein
  • Blood dendritic cell antigen 2
  • CD303 antigen
  • CD303
  • CLEC4C
  • CLECSF11
  • CLECSF11PRO34150
  • CLECSF7
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 11
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 7
  • C-type lectin domain family 4 member C
  • C-type lectin superfamily member 7
  • dendritic cell lectin b
  • Dendritic lectin
  • DLEC
  • DLECMGC125792
  • HECL
  • HECLMGC125793
  • MGC125789
  • PRO34150

Background

Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CLEC4C