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DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
BIIB059
Clonality
Monoclonal
Host
Human
Conjugate
DyLight 405

Order Details

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DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) [DyLight 405] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
CLEC4C
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
CLEC4C
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) [DyLight 405]

  • BDCA2
  • BDCA-2
  • BDCA2MGC125791
  • blood dendritic cell antigen 2 protein
  • Blood dendritic cell antigen 2
  • CD303 antigen
  • CD303
  • CLEC4C
  • CLECSF11
  • CLECSF11PRO34150
  • CLECSF7
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 11
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 7
  • C-type lectin domain family 4 member C
  • C-type lectin superfamily member 7
  • dendritic cell lectin b
  • Dendritic lectin
  • DLEC
  • DLECMGC125792
  • HECL
  • HECLMGC125793
  • MGC125789
  • PRO34150

Background

Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CLEC4C