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DEDD Antibody

Images

 
Biological Strategies: Western Blot: DEDD Antibody [NBP1-31686] - Untreated (-) and treated (+) mouse leukocyte extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with DEDD antibody ...read more
Immunocytochemistry/ Immunofluorescence: DEDD Antibody [NBP1-31686] - Paraformaldehyde-fixed HeLa, using DEDD antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with an alpha Tubulin antibody (Red) ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, RM, XpSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
   

Biological Strategies

     

Order Details

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DEDD Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human DEDD. The exact sequence is proprietary.
Localization
Cytoplasm, Nucleus, nucleolus
Predicted Species
Rat (100%), Xenopus (100%), Bovine (100%), Rhesus Macaque (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DEDD
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for DEDD Antibody

  • CASP8IP1
  • death effector domain containing
  • death effector domain-containing protein
  • Death effector domain-containing testicular molecule
  • death effector domain-containing
  • DEDD1
  • DEDPRO1
  • DEFTKE05
  • FLDED1
  • FLDED-1

Background

This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for DEDD Antibody (NBP1-31686) (0)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for DEDD Antibody (NBP1-31686) (0)

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Secondary Antibodies

 

Isotype Controls

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol DEDD