Orthogonal Strategies: Immunohistochemistry-Paraffin: Cytokeratin 10 Antibody [NBP1-85604] - Analysis in human skin and colon tissues. Corresponding KRT10 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Cytokeratin 10 Antibody [NBP1-85604] - Staining of human lymph node shows no positivity as expected.
Immunohistochemistry-Paraffin: Cytokeratin 10 Antibody [NBP1-85604] - Staining of human skin shows moderate cytoplasmic positivity in epidermal cells.
Immunohistochemistry-Paraffin: Cytokeratin 10 Antibody [NBP1-85604] - Staining of human colon shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: Cytokeratin 10 Antibody [NBP1-85604] - Staining of human kidney shows no positivity in cells in tubules as expected.
This antibody was developed against Recombinant Protein corresponding to amino acids: EQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLE
Predicted Species
Mouse (91%), Rat (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KRT10
Purity
Immunogen affinity purified
Innovator's Reward
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for Cytokeratin 10 Antibody
BCIE
BIE
CK10
CK-10
cytokeratin 10
Cytokeratin-10
EHK
K10keratosis palmaris et plantaris
Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris)
keratin 10
keratin, type I cytoskeletal 10
keratin-10
KPP
Background
This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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