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Cytochrome P450 3A5 Antibody

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Western Blot: Cytochrome P450 3A5 Antibody [H00001577-B01P] - Analysis of CYP3A5 expression in human liver.
Western Blot: Cytochrome P450 3A5 Antibody [H00001577-B01P] - Analysis of CYP3A5 expression in transfected 293T cell line by CYP3A5 polyclonal antibody. Lane1:CYP3A5 transfected lysate(55.22 KDa). Lane2:Non-transfected ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

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Cytochrome P450 3A5 Antibody Summary

Description
Quality control test: Antibody reactive against mammalian transfected lysate.
Immunogen
CYP3A5 (AAH33862.1, 1 a.a. - 502 a.a.) full-length human protein. MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSRDGTLSGE
Specificity
CYP3A5 - cytochrome P450, family 3, subfamily A, polypeptide 5,
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
CYP3A5
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cytochrome P450 3A5 Antibody

  • aryl hydrocarbon hydroxylase
  • CP35
  • CYP3A5
  • CYPIIIA5
  • Cytochrome P450 3A5
  • Cytochrome P450 HLp2
  • cytochrome P-450
  • cytochrome P450, family 3, subfamily A, polypeptide 5
  • cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5
  • Cytochrome P450-PCN3
  • DKFZp686L16231
  • EC 1.14.14.1
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • niphedipine oxidase
  • P450PCN3FLJ31317
  • PCN3
  • xenobiotic monooxygenase

Background

This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CYP3A5
Entrez
Uniprot