ELISA: Human Connexin 26/GJB2 ELISA Kit (Colorimetric) [NBP2-79811] - Samples were spiked with high concentrations of Human Connexin 26/GJB2 and diluted with Reference Standard & Sample Diluent to produce samples with ...read more
ELISA: Human Connexin 26/GJB2 ELISA Kit (Colorimetric) [NBP2-79811] - Standard Curve Reference
Storage of components varies. See protocol for specific instructions.
Kit Components
Components
Biotinylated Detection Ab Diluent
Concentrated Biotinylated Detection Ab (100x)
Concentrated HRP Conjugate (100x)
Concentrated Wash Buffer (25x)
HRP Conjugate Diluent
Micro ELISA Plate (Dismountable)
Plate Sealer
Product Manual
Reference Standard
Sample Diluent
Stop Solution
Substrate Reagent
Alternate Names for Human Connexin 26/GJB2 ELISA Kit (Colorimetric)
beta 2, 26kD (connexin 26)
Connexin 26
CX26
CX26DFNA3
DFNA3
DFNA3A
DFNB1
gap junction protein, beta 2, 26kDa (connexin 26)
gap junction protein, beta 2, 26kDa
GJB2
HID
KID
NSRD1
PPK
Background
Connexin-26 / GJB2 is a gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin-26 belongs to the class 1 (beta) group of connexins. Mutations in Connexin-26 are associated with genetically derived hearing impairments, including autosomal recessive non syndromic deafness.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
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