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Coagulation Factor XIV/Protein C Antibody (PC 7) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
PC 7
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-05113AF350
Alexa Fluor 405
NBP1-05113AF405
Alexa Fluor 488
NBP1-05113AF488
Alexa Fluor 532
NBP1-05113AF532
Alexa Fluor 594
NBP1-05113AF594
Alexa Fluor 647
NBP1-05113AF647
Alexa Fluor 700
NBP1-05113AF700
Alexa Fluor 750
NBP1-05113AF750
Biotin
NBP1-05113B
CoraFluor 1
NBP1-05113CL1
DyLight 350
NBP1-05113UV
DyLight 405
NBP1-05113V
DyLight 488
NBP1-05113G
DyLight 550
NBP1-05113R
DyLight 594
NBP1-05113DL594
DyLight 650
NBP1-05113C
DyLight 680
NBP1-05113FR
DyLight 755
NBP1-05113IR
FITC
NBP1-05113F
HRP
NBP1-05113H
Janelia Fluor 525
NBP1-05113JF525
Janelia Fluor 549
NBP1-05113JF549
Janelia Fluor 635
NBP1-05113JF635
Janelia Fluor 646
NBP1-05113JF646
Janelia Fluor 669
NBP1-05113JF669
PerCP
NBP1-05113PCP
Unconjugated
NBP1-05113
mFluor Violet 450 SE
NBP1-05113MFV450
mFluor Violet 500 SE
NBP1-05113MFV500
mFluor Violet 610 SE
NBP1-05113MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-05113
BSA Free
NBP1-05113
BSA Free
NBP1-05113-0.025mg
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Coagulation Factor XIV/Protein C Antibody (PC 7) [Janelia Fluor® 585] Summary

Immunogen
Recombinant human activated protein C
Epitope
Specific for a conformation-dependent neoepitope that is expressed in activated protein C upon complex-formation with alpha1-antitrypsin.
Specificity
Has specificity for a conformation dependent neoepitope that is expressed in activated protein C upon complex-formation with alpha1-antitrypsin. No reaction is seen to non-complexed alpha1-antitrypsin and only very little cross reaction to protein C zymogen. Note that specificity is calcium dependent.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PROC
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Coagulation Factor XIV/Protein C Antibody (PC 7) [Janelia Fluor® 585]

  • Anticoagulant protein C
  • APC
  • Autoprothrombin IIA
  • Blood coagulation factor XIV
  • Coagulation Factor XIV
  • EC 3.4.21
  • EC 3.4.21.69
  • PC
  • PROC
  • PROC1
  • protein C (inactivator of coagulation factors Va and VIIIa)
  • Protein C
  • vitamin K-dependent protein C

Background

Protein C is a vitamin K-dependent serine protease that is produced in the liver and made up of 2 polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa inhibiting blood coagulation. The molecular weight of the active enzyme is 55 kDa and the normal concentration in human plasma is approximately 1-3 ng/ml while the concentration of the proenzyme is approximately 3 ug/mL due to the very fast turnover.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Coagulation Factor
XIV/Protein C Antibod ...
NBP1-05113JF585
Coagulation Factor XIV/Protein C Antibody (PC 7) [Janelia Fluor® 585]
Species: Hu
Applications: ELISA

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Bioinformatics

Gene Symbol PROC