Coagulation Factor XIV/Protein C Antibody (JM93-61) Summary
Additional Information |
Recombinant Monoclonal Antibody. |
Immunogen |
Recombinant protein within Human Coagulation Factor XIV/Protein C aa 290-380 / 461. (SwissProt: P04070 Human) |
Localization |
Endoplasmic reticulum, Secreted. |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
PROC |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence 1:50-1:200
- Immunohistochemistry
- Immunohistochemistry-Paraffin 1:50-1:200
- Western Blot 1:500
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
TBS (pH7.4), 0.05% BSA, 40% Glycerol |
Preservative |
0.05% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Protein A purified |
Alternate Names for Coagulation Factor XIV/Protein C Antibody (JM93-61)
Background
Protein C is a vitamin K-dependent serine protease that is produced in the liver and made up of 2 polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa inhibiting blood coagulation. The molecular weight of the active enzyme is 55 kDa and the normal concentration in human plasma is approximately 1-3 ng/ml while the concentration of the proenzyme is approximately 3 ug/mL due to the very fast turnover.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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