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Coagulation Factor XIV/Protein C Antibody (390226)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clone
390226
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price
Carrier Free
MAB3349-SP
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Coagulation Factor XIV/Protein C Antibody (390226) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Coagulation Factor XIV/Protein C
Ala43-Pro461
Accession # P04070
Specificity
Detects human Coagulation Factor XIV/Protein C in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) Factor VII, rhFactor X, rhFactor XI, rhThrombin, rhUPA, rhHGFA, rhKallikrein 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, or 15 is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PROC
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 25 ug/mL
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Coagulation Factor XIV/Protein C Antibody (390226)

  • Anticoagulant protein C
  • APC
  • Autoprothrombin IIA
  • Blood coagulation factor XIV
  • Coagulation Factor XIV
  • EC 3.4.21
  • EC 3.4.21.69
  • PC
  • PROC
  • PROC1
  • protein C (inactivator of coagulation factors Va and VIIIa)
  • Protein C
  • vitamin K-dependent protein C

Background

Coagulation factor XIV, also known as Protein C, has anti-coagulation activity by degrading factors VIIIa and Va, which are required for thrombin activation. Protein C deficiency results in hereditary thrombophilia, and a severe recessive form may result in massive thrombosis fatal to patient. The deduced amino acid sequence of human protein C predicts a signal peptide (aa 1‑32), a propeptide (aa 33‑42), and a mature chain (aa 43‑461), which can be converted into two disulfide-linked chains (light: aa 43‑199 and heavy: aa 200‑461). The amino acid sequence of human protein C is 99.8%, 80%, 70%, 69% and 54% identical to that of chimpanzee, canine, rat, mouse and chicken.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Coagulation Factor
XIV/Protein C Antibod ...
MAB3349
Coagulation Factor XIV/Protein C Antibody (390226)
Species: Hu
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Bioinformatics

Gene Symbol PROC
Uniprot