CEACAM6/CD66c Antibody Pair [HRP] Summary
Description |
Solid Phase sandwich ELISA for the quantitative determination of Human CEACAM6/CD66c. |
Additional Information |
Recombinant Monoclonal Antibody |
Specificity |
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human CEACAM6/CD66c. |
Standard Curve Range |
9.34-600 pg/ml (example only; lot dependent) |
Sensitivity |
9.34 pg/ml (example only; lot dependent) |
Assay Type |
Sandwich ELISA |
Sample Volume |
100 ul |
Gene |
CEACAM6 |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
Alternate Names for CEACAM6/CD66c Antibody Pair [HRP]
Background
CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glycoprotein (PSG1-PSG11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. CEACAM 6 expression is strongly up-regulated already during early stages of adenocarcinoma formation e.g. in colon. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are
guaranteed for 6 months from date of receipt.
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