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CEACAM6/CD66c Antibody (439424) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
439424
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3934U-100UG
Alexa Fluor 405
FAB3934V-100UG
Alexa Fluor 488
FAB3934G-100UG
Alexa Fluor 532
FAB3934X
Alexa Fluor 594
FAB3934T-100UG
Alexa Fluor 647
FAB3934R-100UG
Alexa Fluor 700
FAB3934N-100UG
Alexa Fluor 750
FAB3934S-100UG
Allophycocyanin
FAB3934A
Allophycocyanin/Cy7
FAB3934APCCY7
Biotin
FAB3934B
CoraFluor 1
FAB3934CL1
DyLight 350
FAB3934D
DyLight 405
FAB3934E
DyLight 488
FAB3934K
DyLight 550
FAB3934L
DyLight 594
FAB3934M
DyLight 650
FAB3934W
DyLight 680
FAB3934Y
DyLight 755
FAB3934Z
HRP
FAB3934H
Janelia Fluor 525
FAB3934JF525
Janelia Fluor 549
FAB3934I
Janelia Fluor 585
FAB3934JF585
Janelia Fluor 635
FAB3934JF635
Janelia Fluor 669
FAB3934JF669
PE
FAB3934P
PE/Atto594
FAB3934PEATT594
PE/Cy5.5
FAB3934PECY55
PE/Cy7
FAB3934PECY7
PerCP
FAB3934C
Unconjugated
MAB3934
mFluor Violet 450 SE
FAB3934MFV450
mFluor Violet 500 SE
FAB3934MFV500
mFluor Violet 610 SE
FAB3934MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3934
Carrier Free
MAB3934
Carrier Free
FAB3934A
Carrier Free
MAB3934-SP
Carrier Free
FAB3934V-100UG
Carrier Free
FAB3934U-100UG
Carrier Free
FAB3934T-100UG
Carrier Free
FAB3934S-100UG
Carrier Free
FAB3934R-100UG
Carrier Free
FAB3934N-100UG
Carrier Free
FAB3934G-100UG
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CEACAM6/CD66c Antibody (439424) [Janelia Fluor® 646] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human CEACAM-6/CD66c
Lys35-Gly320
Accession # P40199
Specificity
Detects human CEACAM-6/CD66c in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human CEACAM-1, -3, or -5 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CEACAM6
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CEACAM6/CD66c Antibody (439424) [Janelia Fluor® 646]

  • carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific crossreacting antigen)
  • carcinoembryonic antigen-related cell adhesion molecule 6
  • CD66c antigen
  • CD66c
  • CEACAM6
  • CEACAM-6
  • CEAL
  • NCA
  • NCACEAL
  • Non-specific crossreacting antigen
  • Normal cross-reacting antigen

Background

CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glycoprotein (PSG1-PSG11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. CEACAM 6 expression is strongly up-regulated already during early stages of adenocarcinoma formation e.g. in colon. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CEACAM6