CD72.1 Antibody (10-1.D.2) - Azide and BSA Free Summary
Immunogen |
DBA/2 mouse spleen cells |
Specificity |
Mouse CD72.1/Lyb-2.1, 45 kDa |
Isotype |
IgG2b Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
Cd72 |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1:10 - 1:1000
|
Reactivity Notes
Mouse. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
0.1M BBS (pH 8.2) |
Preservative |
No Preservative |
Concentration |
0.5 mg/ml |
Purity |
Protein A or G purified |
Alternate Names for CD72.1 Antibody (10-1.D.2) - Azide and BSA Free
Background
Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (1,2) The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72.1-5
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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