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CD42b/GPIb alpha Antibody (AK2) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, IP
Clone
AK2
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-63790AF350
Alexa Fluor 405
NB100-63790AF405
Alexa Fluor 488
NB100-63790AF488
Alexa Fluor 532
NB100-63790AF532
Alexa Fluor 594
NB100-63790AF594
Alexa Fluor 647
NB100-63790AF647
Alexa Fluor 700
NB100-63790AF700
Alexa Fluor 750
NB100-63790AF750
Allophycocyanin
NB100-63790APC
Allophycocyanin/Cy7
NB100-63790APCCY7
Biotin
NB100-63790B
CoraFluor 1
NB100-63790CL1
DyLight 350
NB100-63790UV
DyLight 405
NB100-63790V
DyLight 488
NB100-63790G
DyLight 550
NB100-63790R
DyLight 594
NB100-63790DL594
DyLight 650
NB100-63790C
DyLight 680
NB100-63790FR
DyLight 755
NB100-63790IR
FITC
NB100-63790F
HRP
NB100-63790H
Janelia Fluor 525
NB100-63790JF525
Janelia Fluor 549
NB100-63790JF549
Janelia Fluor 635
NB100-63790JF635
Janelia Fluor 646
NB100-63790JF646
Janelia Fluor 669
NB100-63790JF669
PE
NB100-63790PE
PE/Atto594
NB100-63790PEATT594
PE/Cy5.5
NB100-63790PECY55
PE/Cy7
NB100-63790PECY7
PerCP
NB100-63790PCP
Unconjugated
NB100-63790
mFluor Violet 450 SE
NB100-63790MFV450
mFluor Violet 500 SE
NB100-63790MFV500
mFluor Violet 610 SE
NB100-63790MFV610
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CD42b/GPIb alpha Antibody (AK2) [Janelia Fluor® 585] Summary

Additional Information
Clone AK2 was used by HLDA to establish CD designation.
Immunogen
Made to Human CD42b
Specificity
Recognises the human CD42b cell surface antigen, also known as platelet glycoprotein GP1B. CD42b is expressed by platelets and megakaryocytes. Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets (1).
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
GP1BA
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:29437579).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CD42b/GPIb alpha Antibody (AK2) [Janelia Fluor® 585]

  • Antigen CD42b-alpha
  • BP1BA
  • BSS
  • CD42b antigen
  • CD42b
  • CD42b-alpha
  • glycoprotein Ib (platelet), alpha polypeptide
  • Glycoprotein Ibalpha
  • GP1B
  • GP1BA
  • GPIb alpha
  • GP-Ib alpha
  • GPIbA
  • GPIb-alpha
  • MGC34595
  • platelet glycoprotein Ib alpha chain
  • platelet membrane glycoprotein 1b-alpha subunit

Background

CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CD42b/GPIb alpha
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NB100-63790JF585
CD42b/GPIb alpha Antibody (AK2) [Janelia Fluor® 585]
Species: Hu
Applications: ELISA, Flow, IP

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Bioinformatics

Gene Symbol GP1BA