Mouse myeloma cell line NS0-derived recombinant human C1q R1/CD93 Ala24-Lys580 Accession # Q9NPY3
Specificity
Detects human C1q R1/CD93 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant mouse C1q R1 is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD93
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
C1q R1 is also known as C1q Rp, Collectin Receptor, and AA4 antigen, and is designated CD93. C1q R1 mediates enhanced phagocytosis by monocytes and macrophages upon interaction with soluble defense collagens including C1q, MBL, and SP-A (1, 2). It is a type I transmembrane glycoprotein expressed on endothelial cells, hematopoietic progenitor cells, platelets, and cells of myeloid origin. C1q R1 has also been identified as a stem cell marker (3, 4).
Kim, T.S. etal. (2000) Mol. Immunol. 37:377.
Dean, Y.D. et al. (2001) Eur. J. Immunol. 31:1370.
Petrenko, O. et al. (1999) Immunity 10:691.
Danet, G.H. et al. (2002) Proc. Natl. Acad. Sci. USA 99:10441.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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