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BRM Antibody (2D12)

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Immunocytochemistry/Immunofluorescence: BRM Antibody (2D12) [H00006595-M06] - Analysis of monoclonal antibody to SMARCA2 on HeLa cell. Antibody concentration 10 ug/ml
Immunocytochemistry/ Immunofluorescence: BRM Antibody (2D12) [H00006595-M06] - Analysis of monoclonal antibody to SMARCA2 on HeLa cell. Antibody concentration 10 ug/ml
ELISA: BRM Antibody (2D12) [H00006595-M06] - Detection limit for recombinant GST tagged SMARCA2 is approximately 0.1ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
2D12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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BRM Antibody (2D12) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
SMARCA2 (NP_003061, 659 a.a. ~ 735 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWM
Specificity
SMARCA2 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SMARCA2
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for BRM Antibody (2D12)

  • ATP-dependent helicase SMARCA2
  • BAF190B
  • BRG1-associated factor 190B
  • BRM
  • BRMFLJ36757
  • EC 3.6.1
  • EC 3.6.4.-
  • global transcription activator homologous sequence
  • hBRM
  • hBRMMGC74511
  • hSNF2a
  • probable global transcription activator SNF2L2
  • Protein brahma homolog
  • SMARCA2
  • SNF2
  • SNF2/SWI2-like protein 2
  • SNF2A
  • SNF2-alpha
  • SNF2L2
  • SNF2L2BAF190
  • SNF2LA
  • SNF2-like 2
  • Sth1p
  • subfamily a, member 2
  • sucrose nonfermenting 2-like protein 2
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A member 2
  • SWI2

Background

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SMARCA2
Entrez
OMIM
Uniprot