BCL11B Antibody

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins. Involved in placental, cardiac, hepatic and embryonic development. NCOA6 is over-expressed in several breast cancer cell lines.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 5 applications: ICC/IF, IF/IHC, IHC, IHC-Fr, IHC-P.

Showing Publications 1 - 7 of 7.

Publications using NB100-2600	Applications	Species
Wang Y, Zhang F, Gao N et al. Differential expression of BCL11b and CDKN2A in CD30-positive peripheral T cell lymphoma: Retrospective study Medicine 2023-11-17 [PMID: 37986346] (IHC-P, Human)	IHC-P	Human
Traunm�ller L, Schulz J, Ortiz R et al. A cell-type-specific alternative splicing regulator shapes synapse properties in a trans-synaptic manner Cell reports 2023-02-28 [PMID: 36862556] (IHC, Mouse)	IHC	Mouse
Bakalar D, O'Reilly JJ, Lacaille H et al. Lack of placental neurosteroid alters cortical development and female somatosensory function Front Endocrinol (Lausanne) 2022-10-13 [PMID: 36313771]
Padella A, Simonetti G, Paciello G, et al. Novel and Rare Fusion Transcripts Involving Transcription Factors and Tumor Suppressor Genes in Acute Myeloid Leukemia Cancers (Basel) 2019-12-05 [PMID: 31817495] (IF/IHC, Human)	IF/IHC	Human
Digilio L, Yap CC, Winckler B. Ctip2-, Satb2-, Prox1-, and GAD65-Expressing Neurons in Rat Cultures: Preponderance of Single- and Double-Positive Cells, and Cell Type-Specific Expression of Neuron-Specific Gene Family Members, Nsg-1 (NEEP21) and Nsg-2 (P19). PLoS One 2015-01-01 [PMID: 26465886] (Rat)		Rat
Carpentier PA, Haditsch U, Braun AE et al. Stereotypical alterations in cortical patterning are associated with maternal illness-induced placental dysfunction. J Neurosci. 2013-10-23 [PMID: 24155294] (IHC-Fr, ICC/IF, Mouse)	IHC-Fr, ICC/IF	Mouse
Beguin S, Crepel V, Aniksztejn L, Becq H, Pelosi B, Pallesi-Pocachard E, Bouamrane L, Pasqualetti M, Kitamura K, Cardoso C, Represa A. An Epilepsy-Related ARX Polyalanine Expansion Modifies Glutamatergic Neurons Excitability and Morphology Without Affecting GABAergic Neurons Development. Cereb Cortex. 2012-05-24 [PMID: 22628459] (IF/IHC, Mouse)	IF/IHC	Mouse

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	IHC-P	Mouse	10/03/2014	View Summary Application Immunohistochemistry-Paraffin Sample Tested mouse brain Species Mouse

Array NB100-2600

• BCL11B Antibodies
• BCL11B Protein