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Azurocidin/CAP37/HBP Antibody (B-K37) [Alexa Fluor® 700]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
B-K37
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 700

Order Details

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Azurocidin/CAP37/HBP Antibody (B-K37) [Alexa Fluor® 700] Summary

Immunogen
Recombinant human Azurocidin/Cap37/HBP
Specificity
recognizes both natural and recombinant human Azurocidin/CAP37/HBP
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
AZU1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Affinity purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Azurocidin/CAP37/HBP Antibody (B-K37) [Alexa Fluor® 700]

  • AZAMP
  • AZU
  • AZU1
  • azurocidin 1
  • Azurocidin
  • CAP37
  • CAP37Heparin-binding protein
  • cationic antimicrobial protein 37
  • HBP
  • HBPCationic antimicrobial protein CAP37
  • HUMAZUR
  • NAZC
  • neutrophil azurocidin

Background

Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol AZU1