PSG3 Products

Description

The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 (PubMed 7851896)). For additional general information about the PSG gene family, see PSG1 (MIM 176390).(supplied by OMIM)

Bioinformatics

Entrez	5671 Human
Uniprot	AAH05924 Human AAH05924.2 Human NM_021016 Human Q16557 Human
Product By Gene ID	5671
Alternate Names	Carcinoembryonic antigen SG5 pregnancy specific beta-1-glycoprotein 3 pregnancy-specific beta-1-glycoprotein 3 Pregnancy-specific glycoprotein 3 PS-beta-G-3 PSBG-3