Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
Recombinant protein encompassing a sequence within the center region of human Transgelin/TAGLN/SM22 alpha. The exact sequence is proprietary. |
Predicted Species |
Porcine (98%), Bovine (97%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
TAGLN |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunohistochemistry-Paraffin
- Western Blot 1:500-1:3000
|
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (87%), Xenopus (80%).
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
No Preservative |
Purity |
Protein A purified |
Alternate Names for Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free
Background
In contrast to fast and slow skeletal muscle cells that fuse and terminally differentiate, smooth muscle cells are able to simultaneously proliferate and express lineage-restricted proteins. One of these proteins, expressed exclusively in smooth muscles, has been referred to as SM22-alpha, a 22 kDa protein with structural similarity to the vertebrate thin filament myofibrillar regulatory protein calponin and the Drosophila muscle protein mp20, neither of which play a direct role in the contractile apparatus.The protein is a transformation and shape-change sensitive actin cross-linking/geling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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