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Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free

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Immunohistochemistry-Paraffin: Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free [NBP3-25726] - Transgelin antibody [HL1270] detects Transgelin protein at cytoplasm by immunohistochemical analysis. ...read more
Immunohistochemistry-Paraffin: Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free [NBP3-25726] - Transgelin antibody [HL1270] detects Transgelin protein by immunohistochemical analysis. Sample: ...read more
Immunohistochemistry-Paraffin: Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free [NBP3-25726] - Transgelin antibody [HL1270] detects Transgelin protein at cytoplasm by immunohistochemical analysis. ...read more
Orthogonal Strategies: Western Blot: Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free [NBP3-25726] - Various whole cell extracts (30 ug) were separated by 15% SDS-PAGE, and the membrane was ...read more
Western Blot: Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free [NBP3-25726] - Various whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with Transgelin antibody ...read more
Immunohistochemistry-Paraffin: Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free [NBP3-25726] - Transgelin antibody [HL1270] detects Transgelin protein at cytoplasm by immunohistochemical analysis. ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, BvSpecies Glossary
Applications WB, IHC
Clone
HL1270
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free
Validated by:
       

Orthogonal Strategies

 

Order Details

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Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Transgelin/TAGLN/SM22 alpha. The exact sequence is proprietary.
Predicted Species
Porcine (98%), Bovine (97%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
TAGLN
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:3000

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (87%), Xenopus (80%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Alternate Names for Transgelin/TAGLN/SM22 alpha Antibody (HL1270) - Azide and BSA Free

  • DKFZp686P11128
  • Protein WS3-10
  • SM22 alpha
  • SM2222 kDa actin-binding protein
  • SMCCDKFZp686B01212
  • Smooth muscle protein 22-alpha
  • TAGLN
  • TAGLN1
  • transgelin variant 2
  • Transgelin
  • WS3-10
  • WS3-10SM22-alpha

Background

In contrast to fast and slow skeletal muscle cells that fuse and terminally differentiate, smooth muscle cells are able to simultaneously proliferate and express lineage-restricted proteins. One of these proteins, expressed exclusively in smooth muscles, has been referred to as SM22-alpha, a 22 kDa protein with structural similarity to the vertebrate thin filament myofibrillar regulatory protein calponin and the Drosophila muscle protein mp20, neither of which play a direct role in the contractile apparatus.The protein is a transformation and shape-change sensitive actin cross-linking/geling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TAGLN