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TRAILR1/TNFRSF10A Antibody (69036) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, CyTOF-ready
Clone
69036
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB347U-100UG
Alexa Fluor 405
FAB347V-100UG
Alexa Fluor 488
FAB347G-100UG
Alexa Fluor 532
FAB347X
Alexa Fluor 594
FAB347T-100UG
Alexa Fluor 647
FAB347R-100UG
Alexa Fluor 700
FAB347N-100UG
Alexa Fluor 750
FAB347S-100UG
Allophycocyanin
FAB347A-100
Allophycocyanin
FAB347A-025
Allophycocyanin/Cy7
FAB347APCCY7
Biotin
FAB347B
DyLight 350
FAB347D
DyLight 405
FAB347E
DyLight 488
FAB347K
DyLight 550
FAB347L
DyLight 594
FAB347M
DyLight 650
FAB347W
DyLight 680
FAB347Y
DyLight 755
FAB347Z
FITC
FAB347F
HRP
FAB347H
Janelia Fluor 549
FAB347I
PE/Atto594
FAB347PEATT594
PE/Cy5.5
FAB347PECY55
PE/Cy7
FAB347PECY7
Unconjugated
MAB347-100
mFluor Violet 450 SE
FAB347MFV450
mFluor Violet 500 SE
FAB347MFV500
mFluor Violet 610 SE
FAB347MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB347-100
Carrier Free
MAB347-SP
Carrier Free
MAB347-500
Carrier Free
MAB347-100
Carrier Free
FAB347A-100
Carrier Free
FAB347A-025
Carrier Free
FAB347V-100UG
Carrier Free
FAB347U-100UG
Carrier Free
FAB347T-100UG
Carrier Free
FAB347S-100UG
Carrier Free
FAB347R-100UG
Carrier Free
FAB347N-100UG
Carrier Free
FAB347G-100UG
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TRAILR1/TNFRSF10A Antibody (69036) [Janelia Fluor® 646] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human TRAIL R1/TNFRSF10A
Ala24-Asn239
Accession # AAC51226
Specificity
Detects recombinant human TRAIL R1/TNFRSF10A in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) TRAIL R2, rhTRAIL R3, rhTRAIL R4, or rhDcR3 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10A
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TRAILR1/TNFRSF10A Antibody (69036) [Janelia Fluor® 646]

  • APO2
  • CD261 antigen
  • CD261
  • cytotoxic TRAIL receptor
  • Death receptor 4
  • DR4 TRAIL receptor 1
  • DR4
  • TNF-related apoptosis inducing ligand receptor 1
  • TNF-related apoptosis-inducing ligand receptor 1
  • TNFRSF10A
  • TRAIL R1
  • TRAILR1
  • TRAIL-R1
  • TRAILR-1
  • TRAILR1MGC9365
  • tumor necrosis factor receptor superfamily member 10A
  • tumor necrosis factor receptor superfamily, member 10a

Background

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNFRSF10A