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TRA-1-60® Antibody (TRA-1-60) [NL493]

Images

 
The stem cell marker TRA-1-60(R) was visualized in live BG01V human embryonic stem cells using a GloLIVE NL493-conjugated Mouse Anti-Human TRA-1-60(R) Monoclonal Antibody (Catalog # NLLC4770G; green). The nuclei were ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clone
TRA-1-60
Clonality
Monoclonal
Host
Mouse
Conjugate
NL493

TRA-1-60® Antibody (TRA-1-60) [NL493] Summary

Additional Information
50X Concentration, Azide Free
Specificity
Detects human TRA‑1‑60(R).
Isotype
IgM
Clonality
Monoclonal
Host
Mouse
Gene
PODXL
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TRA-1-60(R) Antibody (TRA-1-60) [NL493]

  • RA160
  • TRA160(R)
  • TRA-1-60(R)
  • tra61

Background

TRA-1-60 is a monoclonal antibody raised against a cell surface antigen of human embryonal carcinoma (EC) cells (1). The TRA-1-60 epitope is also found on human embryonic stem (ES) cells and primordial germ cells, and TRA-1-60 serves as a serum marker in patients with germ cell tumors (2‑4). Investigation into the identity of the TRA-1-60 epitope demonstrated that it is a carbohydrate carried by a cell surface, sialylated, keratan sulfate proteoglycan (5). Subsequent evidence implicated podocalyxin as a carrier for the TRA-1-60 epitope (6).

  1. Andrews, P. et al. (1984) Hybridoma 3:347.
  2. Thomson, J. et al. (1998) Science 282:1145.
  3. Giwercman, A. et al. (1993) Cancer 72:1308.
  4. Marrink, J. et al. (1991) Int. J. Cancer 49:368.
  5. Badcock, G. et al. (1999) Cancer Res. 59:4715.
  6. Schopperle, W. and W. DeWolf (2007) Stem Cells 25:723.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TRA-1-60(R) Antibody (NLLC4770G) (0)

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FAQs for TRA-1-60(R) Antibody (NLLC4770G) (0)

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Secondary Antibodies

 

Isotype Controls

Additional TRA-1-60(R) Products

Array NLLC4770G

Blogs on TRA-1-60(R)

There are no specific blogs for TRA-1-60(R), but you can read our latest blog posts.
mFluor Violet Conjugated Antibodies

Contact Information

Product PDFs

Calculators

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Bioinformatics

Gene Symbol PODXL