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SFRS8 Antibody

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Independent Antibodies: Western Blot: SFRS8 Antibody [NB100-55245] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-SFRS8/SWAP antibody ...read more
Immunohistochemistry: SFRS8 Antibody [NB100-55245] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti- SFRS8/SWAP used at a dilution of 1:200 (1ug/ml). Detection: DAB
Immunohistochemistry-Paraffin: SFRS8 Antibody [NB100-55245] - FFPE section of human lung carcinoma. Affinity purified rabbit anti-SFRS8/SWAP used at a dilution of 1:100.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
Validated by:
 

Independent Antibodies

       

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SFRS8 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 500 and 550 of human splicing factor, arginine/serine-rich 8 using the numbering given in entry NP_004583.2 (GeneID 6433).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SFSWAP
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SFRS8 Antibody

  • Drosophila homolog)
  • Drosophila)
  • SFRS8
  • splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog
  • splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot
  • Splicing factor, arginine/serine-rich 8
  • splicing factor, suppressor of white-apricot homolog (Drosophila)
  • splicing factor, suppressor of white-apricot homolog
  • Suppressor of white apricot protein homolog
  • SWAPMGC167082

Background

SFRS8 regulates the splicing of CD45, a protein which through alternative splice variants, has an essential role in activating T cells. T cells are involved in the pathogenesis of atopic diseases such as asthma, making SFRS8 a very interesting candidate gene in the region. SFRS8 could act as a weak predisposing gene for asthma. The basic functions of SFRS8 are the mediation of protein-protein interactions within the intron during spliceosome assembly, independently binding to exonic enhancer sequences, and recruiting components to adjacent introns for splice-site recognition and alternative splicing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SFSWAP
Entrez
Uniprot